Tirzepatide (same active ingredient as Mounjaro®), for weight loss

Zepbound® (tirzepatide) Injection

  • Lose 20% of your body weight on average in 1 year*. See safety info below.

  • New FDA-approved medication for weight loss (same active ingredient as Mounjaro)

  • Targets two hormone receptors (GLP-1 and GIP) to maximize weight loss

*Patients without diabetes and with BMI ≥30, or BMI ≥27 plus a weight-related condition, lost an average of 20% of their body weight by 1 year in a 72-week trial studying the highest maintenance dose of Zepbound (15 mg), when paired with diet and exercise changes (compared to 3% with diet and exercise alone).

15-20% stat

Select your current weight


Weight you could lose (lbs):


*In a 68- and 72-week clinical trial studying Wegovy (2.4 mg) and Zepbound (15 mg) in patients without diabetes and with BMI ≥30, or BMI ≥27 with a weight-related condition, the average weight loss was 15% and 20%, when paired with diet and exercise changes (compared to 2.4% and 3.1%, respectively, with diet and exercise alone).

How Ro helps you lose weight

We’re pushing every day to get medication to our patients faster. Here’s a quick rundown: It takes 4-6 weeks to start if you’re not using insurance. If your provider orders a lab test, it may extend the timeline depending on how quickly you complete the labs. If you’d like to use your insurance, it can take an additional 2-3 weeks to determine coverage. We’ll handle the paperwork and work hard to get that coverage for you.

Getting started

Answer health questions and complete your online visit

Share your health history and weight loss goals with us online to get started. A Ro-affiliated provider will review your answers and get back to you within a few days. Depending on your health review, a provider may order a metabolic lab test before moving forward with treatment.

After reviewing your results, your provider will determine if you’re eligible for medication. If you are, they’ll tailor a program with prescription treatment best suited to your unique biology.

If you'd like to try to use insurance, our concierge partner connects with your insurance company to help get the cost of medication covered. If coverage is denied, we'll help you understand your options, including paying cash.

Ongoing monthly care

If you're prescribed compounded semaglutide, our partner pharmacy will ship your medication in 1-4 days. If you're prescribed a branded GLP-1 medication, you'll get your prescription from your preferred pharmacy. Medication costs are not included.

You’ll have everything you need during treatment, including on-demand provider access via video or messaging, medication management, and ongoing refill support.


Dr. Pepper lost 30 lbs in 1 year

“I started losing weight almost immediately. To me, truly, this has been a game-changer.”

Dr. Pepper Ro Ambassador who inspired the Body Program, after taking GLP-1 medication


Stacie lost 49 lbs in 6 months

“I used to constantly crave food in general. I was always hungry before starting the Body Program.”

Stacie Ro member after taking GLP-1 medication

Meet our expert

From diagnosis to delivery, our healthcare providers are with patients every step of the way.

Hear from Body Program members

Ro Body Program members taking branded GLP-1 medications were paid for their testimonials.

Zepbound FAQs

From the experts at ro

Read more about Zepbound

Dr Steve Silvestro, Ro

Zepbound 101

How does Zepbound work?

Zepbound mimics two naturally occurring hormones (GLP-1 and GIP) in your body to help you regulate your metabolism. This slows digestion and makes you feel full faster and longer. It also communicates with the part of your brain in charge of hunger to help you regulate how much you eat. On average, patients lost 20% of their body weight in a year using the highest dose of  Zepbound when combined with healthy lifestyle changes. 

What is Zepbound’s dosing?

If prescribed, you’ll start on the lowest dose (2.5 mg) for the first four weeks, and then work with your provider to slowly increase your dose every four weeks until you reach a steady dose that works best for you.

How do you take Zepbound?

Zepbound is a once-weekly injection that comes in a pre-filled, single-dose pen. If prescribed, you’ll receive detailed instructions from your provider on how to inject it in your stomach, arm, or thigh.

How much weight can I expect to lose with Zepbound?

In clinical trials, patients lost an average of 20% of their body weight in a year when they combined the highest dose of Zepbound with healthy lifestyle changes.

Who can use Zepbound? Who shouldn’t use it?

Zepbound is approved for weight loss in adults who either have a BMI of at least 30 or a BMI of at least 27 with a weight-related condition, like high blood pressure, type 2 diabetes, or cardiovascular disease.

How are side effects for Zepbound different from Ozempic or Wegovy?

The side effects of Zepbound are similar to Ozempic and Wegovy. However, birth control pills have been shown to be less effective when taking Zepbound. If you’re considering treatment with Zepbound, tell your provider about what contraception you’re taking. For more information about side effects, learn more here: ro.co/safety-info/zepbound

Will insurance cover Zepbound?

Some health plans cover Zepbound for weight loss, but coverage and copay amounts vary. Plans may also require prior authorization before approving coverage. If you’re interested in paying with insurance, we’ll work with your provider to help you get coverage.