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DesignBaselineWeight change at end of treatment

Mean change in body weight from baseline. ITT = treatment-regimen estimand, Efficacy = on-treatment estimand. Comparator Δ = change in the placebo or comparator arm. † Change from the start of the run-in or lead-in. Hover a value for its reference.

A note on interpreting comparisons: This tool is intended to help explore findings across clinical trials and provide context for understanding the broader evidence landscape. While side-by-side results can help identify patterns and directional trends, apparent differences should not be interpreted as evidence that one treatment is more effective or better tolerated than another. Direct head-to-head randomized trials provide the strongest evidence for treatment comparisons.

Data as of ·
Methods

Drugs, studies and results are compiled from trial registries (ClinicalTrials.gov, EU CTIS and others), peer-reviewed publications, and company and regulator announcements. Each value carries its source.

Weight change is the mean % change in body weight from randomisation at the stated week, shown by estimand (ITT / treatment-regimen, or efficacy / on-treatment) as reported. n/r means not reported.

·More from Ro Research Labsn/r not reported