Key takeaways
Low testosterone can contribute to erectile dysfunction (ED), but it's rarely the direct cause. 20%–40% of people with ED also have low testosterone, yet many people with low T don’t have trouble getting or keeping erections.
Vascular conditions such as high blood pressure, diabetes, and clogged arteries are far more common causes of ED than low testosterone alone.
Treatments such as sildenafil (Viagra) and tadalafil (Cialis) can help with ED regardless of testosterone status.
Testosterone replacement therapy (TRT) may address related symptoms like low libido and fatigue if low testosterone is confirmed.
Here's what we'll cover
Here's what we'll cover
Here's what we'll cover
Key takeaways
Low testosterone can contribute to erectile dysfunction (ED), but it's rarely the direct cause. 20%–40% of people with ED also have low testosterone, yet many people with low T don’t have trouble getting or keeping erections.
Vascular conditions such as high blood pressure, diabetes, and clogged arteries are far more common causes of ED than low testosterone alone.
Treatments such as sildenafil (Viagra) and tadalafil (Cialis) can help with ED regardless of testosterone status.
Testosterone replacement therapy (TRT) may address related symptoms like low libido and fatigue if low testosterone is confirmed.
If you have erectile dysfunction (ED), you might be wondering: Does low testosterone cause ED? Low testosterone (aka low T) can play a role, but it's rarely the main cause.
Conditions that affect blood flow, such as diabetes and high blood pressure, are more common drivers of ED. When low T does impact erections, it usually shows up through reduced libido. However, testosterone also helps keep the blood vessels and smooth muscle in the penis healthy.
Read on for a closer look at the connection between low testosterone and ED, including how low testosterone can affect erections, treatment options, and more.
Does low testosterone cause ED?
Low testosterone can contribute to ED, but it’s unlikely to be the only cause. They are separate conditions that can overlap, but having one doesn't mean you'll have the other.
Here's why: An erection depends on healthy blood flow, working nerves, and relaxed muscles in the penis. Testosterone supports several parts of that process, from the desire that gets things started to the blood vessel health that keeps things working. When levels are low, one or more of those steps can be affected.
Estimates of how many people with ED also have low testosterone vary widely, depending on the population studied and the threshold used to define low T.
But that doesn't mean low testosterone is the reason for their ED. Many people with low T still get and keep erections just fine, and plenty of people with ED have testosterone levels in the normal range.
The rate of low T among people with ED has been estimated at 20%–40%, though results vary. The number depends on where the cutoff for “low” is set, whether testosterone is tested more than once (which is the standard approach), and whether symptoms are also required for diagnosis.
Stricter definitions tend to produce lower estimates.
What is low testosterone?
Low testosterone, or hypogonadism, is commonly defined as occurring when testosterone levels fall below 300 nanograms per deciliter (ng/dL) on two morning blood tests, and symptoms are present. The exact cutoff can vary by age, and some providers use slightly different numbers. But what matters most is low levels paired with symptoms.
Levels generally start to decline as early as a person's 20s, falling roughly 1%–2% per year. The rate varies from person to person and is influenced by overall health, weight, and other factors, not just age. That slow decline is normal; low T is only diagnosed when levels are consistently low and causing symptoms.
Low testosterone symptoms
Low T doesn't always look the same from person to person. Some individuals notice one or two changes; others experience several. Common low testosterone symptoms include:
ED
Low sex drive
Fatigue and low energy
Loss of facial and body hair
Decreased muscle mass
Depressed mood or irritability
Weight gain (often increased body fat, especially around the midsection)
Difficulty concentrating
Poor sleep
Decreased sperm production
Anemia (low red blood cell count)
Decreased bone density
Many of these symptoms can also be caused by other conditions, including diabetes, obesity, and hypothyroidism. That's one reason blood testing is important — symptoms alone aren't enough to confirm low T.
How does low testosterone affect erections?
Low testosterone can affect erections through several paths, from reduced desire to changes in blood vessel health.
The most direct path, though, is through libido. When testosterone is low, the desire for sex often drops. Without that desire, the arousal needed to trigger an erection may not happen. It's not that the body can't produce an erection; it's that the signal to start one never gets sent.
If you're dealing with low desire, you might be tempted to try over-the-counter libido pills. But these supplements are not regulated by the US Food and Drug Administration (FDA) and lack scientific evidence supporting their efficacy or safety. You’re better off talking to your healthcare provider to see if there is an underlying cause that can be addressed.
Low T can also contribute to structural changes in penile tissue that affect erectile function over time. Testosterone also supports nitric oxide production. Nitric oxide is a chemical that relaxes blood vessels in the penis, allowing blood to flow in. When testosterone drops, the body may produce less of it, making the process less efficient.
Low T can also lead to tiredness, low mood, and less drive to be active — all of which can make having sex unappealing.
Over time, less physical activity may lead to weight gain. And weight gain can raise the risk of conditions that directly cause ED, like diabetes, high blood pressure, and heart disease.
Excess body fat can also make low T worse. Fat tissue converts testosterone into estrogen, which can lower the amount of testosterone in the bloodstream. This can create a cycle in which low T leads to weight gain, and weight gain leads to worsened low T.
What actually causes most ED
Most cases of ED come down to blood flow rather than hormones.
An erection happens when blood flows into the penis and stays there. Anything that gets in the way of that process can lead to ED. The most common causes of the condition include:
High blood pressure: Hypertension harms blood vessel walls and limits blood flow over time.
Atherosclerosis: Plaque buildup in the arteries narrows blood vessels and cuts off flow.
Diabetes: High blood sugar can damage both nerves and blood vessels needed for erections.
Obesity: Extra weight raises inflammation and can harm blood vessels in the penis, while also lowering testosterone.
Mental health factors: Stress, anxiety, and depression can block arousal and make it harder to get or keep an erection.
Medications: Some drugs, including certain blood pressure meds and antidepressants, can affect erections as a side effect.
Often, more than one of these factors is at play simultaneously to cause ED.
Does testosterone help with ED?
Whether testosterone replacement therapy (TRT) can help with ED depends on what's behind the erectile problems in the first place.
If low testosterone is the main reason, meaning low desire is the core issue, and there's no major blood vessel or nerve damage, then bringing testosterone back to normal levels may help with both libido and erections.
But here's the key: Raising testosterone above the normal range doesn't help erections and carries risks. These include higher red blood cell counts (which may increase the risk of blood clots) and acne.
TRT can also suppress sperm production, in some cases significantly, which is an important consideration if you're planning to have children. Testicular shrinkage and sleep apnea are other possible side effects.
There's also limited proof that treating low testosterone alone can fully resolve ED when other causes, such as blood vessel damage from diabetes or high blood pressure, are involved. In those cases, TRT may help with desire and potentially some aspects of wellbeing, such as mood and energy.
At the end of the day, whether testosterone replacement therapy may be a fit for you and potentially help your ED is a conversation that you should have with a healthcare provider.
How to treat ED when low testosterone is involved
When both low testosterone and ED are present, they're usually treated as overlapping but independent conditions.
Treating low testosterone
If blood tests confirm low T, a healthcare provider may suggest TRT. Options include skin patches, gels, shots, or pellets placed under the skin.
For people with low T who want to keep their fertility, a medication called clomiphene (Clomid) may be an option worth discussing with a healthcare provider.
Taking clomiphene for low T is an off-label use of the drug, which was originally approved for female infertility. Unlike TRT, the medication works by pushing the body to make more of its own testosterone while preserving or even improving sperm counts.
Treating ED
No matter your testosterone levels, PDE5 inhibitors are typically the go-to treatment for ED. These prescription drugs work by helping the muscles and blood vessels in the penis relax so blood can flow in. Options include:
Vardenafil (generic; formerly sold as Levitra)
Avanafil (Stendra)
Certain PDE5 inhibitors can also be found in other non-pill formulations. Ro, for example, offers the following (if prescribed):
Ro Sparks*, a fast-acting, dissolvable lozenge that contains both sildenafil and tadalafil (the active ingredients in Viagra and Cialis, respectively). It can start to work in 15 minutes (after dissolving) and last up to 36 hours.
Daily Rise Gummies*, fruit-flavored gummies made with a daily dose of tadalafil. Designed to be taken every day, the treatment can work continuously — no planning of sexual activity required.
Some research suggests that pairing TRT with PDE5 inhibitors may help in cases where PDE5 inhibitors alone haven’t been effective, though overall evidence for the combination is mixed. This is worth discussing with a healthcare provider.
Other options include vacuum devices (aka penis pumps) and, in more severe cases, penile injections. Some people also look into procedures like the Priapus shot, though the best available evidence has not shown it to be more effective than placebo.
*Though these particular formulations are not FDA-approved, their active ingredients have been individually approved for the treatment of ED.
Lifestyle changes
Healthy habits can support both T levels and erectile function:
Exercise regularly: Physical activity improves cardiovascular health and may help boost testosterone.
Maintain a healthy weight: Excess body fat can lower testosterone and increase ED risk. Weight loss may improve both.
Eat a balanced diet: Foods rich in healthy fats, zinc, and leafy greens may support hormone production. A testosterone support supplement may also offer some benefits.
Manage stress: Chronic stress raises cortisol levels, which can suppress testosterone.
How to get tested for low testosterone
If you think low T might be playing a role in your ED, the first step is a blood test.
Testosterone levels change throughout the day and are highest in the morning. That's why testing is usually done in the morning on two separate days when you’re fasting. One low reading isn't enough for a diagnosis. It needs to be confirmed with a second test.
Normal testosterone levels for adults generally fall between approximately 300 and 1,000 ng/dL, though what counts as "normal" can depend on your age and the lab running the test.
A healthcare provider may also check other hormones, like luteinizing hormone (LH) and prolactin. These can help identify the root cause of low testosterone — whether the problem is in the testicles, the pituitary gland, or somewhere else.
Bottom line: can low testosterone cause ED?
So, does low testosterone cause ED? It can be part of the picture, but it's rarely the whole story. Here’s what to keep in mind:
Low T can affect libido and tissue health. Low testosterone tends to lower your desire for sex, which can make erection problems worse. It can also directly affect blood flow and tissue health in the penis.
Vascular damage can drive ED. Blood vessel damage from conditions like diabetes and high blood pressure is behind many cases of ED, even when low T is also present.
Treatment may need two tracks. If blood tests confirm low T, treating it may help restore sex drive and energy, but you could still benefit from a separate medication like sildenafil or tadalafil for erections.
Healthy lifestyle practices can support both conditions. Habits, such as regular exercise, consistent sleep, and maintaining a healthy weight, can help you maintain adequate testosterone levels and reduce or prevent ED at the same time.
A healthcare provider can run a simple blood test to check your testosterone levels and help you figure out what's going on. The sooner you get answers, the sooner you can start feeling better.
Frequently asked questions (FAQs)
What are the symptoms of low testosterone?
The symptoms of low testosterone include low sex drive, ED, fatigue, loss of body hair, decreased muscle mass, mood changes, weight gain, poor sleep, and reduced sperm production.
These symptoms overlap with other conditions, so blood tests are needed to confirm low T.
Can low testosterone cause impotence?
Yes, low testosterone can contribute to impotence, but it's rarely the main cause. Low T is best known for reducing desire, which can make it harder to get aroused enough to trigger an erection. Most impotence is caused by vascular conditions like high blood pressure or diabetes, rather than low T alone.
Can you have ED with normal testosterone levels?
Yes, you can have ED with normal testosterone levels. Most people with ED have levels in the normal range. ED is most commonly caused by vascular conditions that affect blood flow to the penis, psychological factors, or medication side effects — none of which require low testosterone to be present.
Will testosterone therapy fix my ED?
Maybe. Testosterone therapy may help resolve your ED if low T is confirmed and reduced desire is the main issue. However, ED is often driven by vascular or other factors that require separate treatment, like PDE5 inhibitors.
A healthcare provider can help figure out whether TRT, ED medication, or both is the right fit.
What is the connection between low T and ED?
The connection between low T and ED works on multiple levels. Low T reduces libido, which can prevent the arousal needed to trigger an erection. It can also affect blood vessels and tissue in the penis directly.
Low T may also lead to fatigue, mood changes, and weight gain, all of which increase ED risk. But the two conditions are separate, and having one doesn't guarantee the other.
How do I know if my ED is caused by low testosterone?
The only way to know if your ED is being caused directly by low T is through blood testing. If your total testosterone is below around 300 ng/dL on two separate morning tests (drawn when you are fasting) and you're also experiencing other low T symptoms (like reduced sex drive and fatigue), low T may be a contributing factor.
A healthcare provider can evaluate your full picture and recommend testing.
DISCLAIMER
If you have any medical questions or concerns, please talk to your healthcare provider. The articles on Health Guide are underpinned by peer-reviewed research and information drawn from medical societies and governmental agencies. However, they are not a substitute for professional medical advice, diagnosis, or treatment.
Viagra Important Safety Information: Read more about serious warnings and safety info.
Cialis Important Safety Information: Read more about serious warnings and safety info.
References
Alkhayal, A., Mahzari, M., Alhammadi, A. S., et al. (2023). Prevalence of hypogonadism symptoms among males with hypothyroidism at a tertiary hospital: A cross-sectional study. Cureus, 15(12), e50255. doi: 10.7759/cureus.50255. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10711326/
Basheer, B., Ila, V., Barros, R., et al. (2025). Management of adverse effects in testosterone replacement therapy. International Brazilian Journal of Urology, 51(3), e20259904. doi: 10.1590/S1677-5538.IBJU.2025.9904. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC12052019/
Bhasin, S., Brito, J. P., Cunningham, G. R., et al. (2018). Testosterone therapy in men with hypogonadism: An Endocrine Society clinical practice guideline. Journal of Clinical Endocrinology & Metabolism, 103(5), 1715–1744. doi: 10.1210/jc.2018-00229. Retrieved from https://pubmed.ncbi.nlm.nih.gov/29562364/
Cho, J. W. & Duffy, J. F. (2019). Sleep, sleep disorders, and sexual dysfunction. World Journal of Men's Health, 37(3), 261–275. doi: 10.5534/wjmh.180045. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704301/
Corona, G. & Maggi, M. (2022). The role of testosterone in male sexual function. Reviews in Endocrine and Metabolic Disorders, 23(6), 1159–1172. doi: 10.1007/s11154-022-09748-3. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC9789013/
Crawford, E. D., Poage, W., Nyhuis, A., et al. (2015). Measurement of testosterone: How important is a morning blood draw? Current Medical Research and Opinion, 31(10), 1911–1914. doi: 10.1185/03007995.2015.1082994. Retrieved from https://pubmed.ncbi.nlm.nih.gov/26360789/
de Almeida Ferreira, M. & Mendonça, J. A. (2022). Long-term testosterone replacement therapy reduces fatigue in men with hypogonadism. Drugs in Context, 11, 2021-8-12. doi: 10.7573/dic.2021-8-12. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC8823386/
Desai, A., Yassin, M., Cayetano, A., et al. (2022). Understanding and managing the suppression of spermatogenesis caused by testosterone replacement therapy (TRT) and anabolic–androgenic steroids (AAS). Therapeutic Advances in Urology, 14, 17562872221105017. doi: 10.1177/17562872221105017. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC9243576/
Fernandez, C. J., Chacko, E. C., & Pappachan, J. M. (2019). Male obesity-related secondary hypogonadism – Pathophysiology, clinical implications and management. European Endocrinology, 15(2), 83–90. doi: 10.17925/EE.2019.15.2.83. Retrieved from https://pubmed.ncbi.nlm.nih.gov/31616498/
Genchi, V. A., Rossi, E., Lauriola, C., et al. (2022). Adipose tissue dysfunction and obesity-related male hypogonadism. International Journal of Molecular Sciences, 23(15), 8194. doi: 10.3390/ijms23158194. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC9330735/
Gerbild, H., Larsen, C. M., Graugaard, C., et al. (2018). Physical activity to improve erectile function: A systematic review of intervention studies. Sexual Medicine, 6(2), 75–89. doi: 10.1016/j.esxm.2018.02.001. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960035/
Gur, S., Alzweri, L., Yilmaz-Oral, D., et al. (2020). Testosterone positively regulates functional responses and nitric oxide expression in the isolated human corpus cavernosum. *Andrology, *8(6), 1824–1833. doi: 10.1111/andr.12866. Retrieved from https://pubmed.ncbi.nlm.nih.gov/32672414/
He, Z., Yin, G., Li, Q. Q., et al. (2021). Diabetes mellitus causes male reproductive dysfunction: A review of the evidence and mechanisms. In Vivo, 35(5), 2503–2511. doi: 10.21873/invivo.12531. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC8408700/
Hernández-Cerda, J., Bertomeu-González, V., Zuazola, P., et al. (2020). Understanding erectile dysfunction in hypertensive patients: The need for good patient management. Vascular Health and Risk Management, 16, 231–239. doi: 10.2147/VHRM.S223331. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC7297457/
Jung, J., Jo, H. W., Kwon, H., et al. (2014). Clinical neuroanatomy and neurotransmitter-mediated regulation of penile erection. International Neurourology Journal, 18(2), 58–62. doi: 10.5213/inj.2014.18.2.58. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076481/
Leslie, S. W. & Sooriyamoorthy, T. (2024). Erectile dysfunction. StatPearls. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK562253/
Liu, Y., Cao, Y., Zhao, B., et al. (2020). Do testosterone supplements enhance response to phosphodiesterase 5 inhibitors in men with erectile dysfunction and hypogonadism: A systematic review and meta-analysis. Translational Andrology and Urology, 9(2), 618–628. doi: 10.21037/tau.2020.01.13. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215032/
Lowy, M. & Ramanathan, V. (2022). Erectile dysfunction: Causes, assessment, and management options. Australian Prescriber, 45(5), 159–161. doi: 10.18773/austprescr.2022.051. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584785/
Maiorino, M. I., Bellastella, G., & Esposito, K. (2015). Lifestyle modifications and erectile dysfunction: What can be expected? Asian Journal of Andrology, 17(1), 5–10. doi: 10.4103/1008-682X.137687. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC4291878/
Millar, A. C., Lau, A. N. C., Tomlinson, G., et al. (2016). Predicting low testosterone in aging men: A systematic review. CMAJ, 188(13), E321–E330. doi: 10.1503/cmaj.150262. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC5026531/
Moon, K. H., Park, S. Y., & Kim, Y. W. (2019). Obesity and erectile dysfunction: From bench to clinical implication. World Journal of Men's Health, 37(2), 138–147. doi: 10.5534/wjmh.180026. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC6479091/
Mulhall, J. P., Trost, L. W., Brannigan, R. E., et al. (2018). Evaluation and management of testosterone deficiency: AUA guideline. The Journal of Urology, 200(2), 423–432. doi: 10.1016/j.juro.2018.03.115. Retrieved from https://pubmed.ncbi.nlm.nih.gov/29601923/
O'Donnell, L. & Smith, L. B. (2026). Endocrinology of the testis and spermatogenesis. In K. R. Feingold et al. (Eds.), Endotext. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK279031/
Panchatsharam, P. K., Durland, J., & Zito, P. M. (2023). Physiology, erection. StatPearls. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK513278/
Qaseem, A., Horwitch, C. A., Vijan, S., et al. (2020). Testosterone treatment in adult men with age-related low testosterone: A clinical guideline from the American College of Physicians. Annals of Internal Medicine, 172(2), 126–133. doi: 10.7326/M19-0882. Retrieved from https://pubmed.ncbi.nlm.nih.gov/31905405/
Rajfer, J. (2000). Relationship between testosterone and erectile dysfunction. Reviews in Urology, 2(2), 122–128. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC1476110/
Rizk, P. J., Kohn, T. P., Pastuszak, A. W., et al. (2017). Testosterone therapy improves erectile function and libido in hypogonadal men. Current Opinion in Urology, 27(6), 511–515. doi: 10.1097/MOU.0000000000000442. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC5649360/
Shigehara, K., Izumi, K., Kadono, Y., et al. (2021). Testosterone and bone health in men: A narrative review. Journal of Clinical Medicine, 10(3), 530. doi: 10.3390/jcm10030530. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC7867125/
Sizar, O., Leslie, S. W., & Pico, J. (2023). Androgen replacement. StatPearls. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK534853/
Tsujimura, A., Hiramatsu, I., Aoki, Y., et al. (2017). Atherosclerosis is associated with erectile function and lower urinary tract symptoms, especially nocturia, in middle-aged men. Prostate International, 5(2), 65–69. doi: 10.1016/j.prnil.2017.01.006. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448724/
U.S. Food and Drug Administration (FDA). (2018). Highlights of prescribing information: Cialis (tadalafil) tablets, for oral use. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021368s030lbl.pdf
Vasan, S. S., Pandey, S., Rao, S. T. S., et al. (2025). Association of sexual health and mental health in erectile dysfunction: Expert opinion from the Indian context. Cureus, 17(1), e77851. doi: 10.7759/cureus.77851. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC11845324/
Watson, N. F., Badr, M. S., Belenky, G., et al. (2015). Recommended amount of sleep for a healthy adult: A joint consensus statement of the American Academy of Sleep Medicine and Sleep Research Society. Sleep, 38(6), 843–844. doi: 10.5665/sleep.4716. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC4434546/
Wheeler, K. M., Sharma, D., Kavoussi, P. K., et al. (2019). Clomiphene citrate for the treatment of hypogonadism. Sexual Medicine Reviews, 7(2), 272–276. doi: 10.1016/j.sxmr.2018.10.001. Retrieved from https://pubmed.ncbi.nlm.nih.gov/30522888/
Zamir, A., Ben-Zeev, T., & Hoffman, J. R. (2021). Manipulation of dietary intake on changes in circulating testosterone concentrations. Nutrients, 13(10), 3375. doi: 10.3390/nu13103375. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538516/
Zhu, A., Andino, J., Daignault-Newton, S., et al. (2022). What is a normal testosterone level for young men? Rethinking the 300 ng/dL cutoff for testosterone deficiency in men 20–44 years old. The Journal of Urology, 208(6), 1295–1302. doi: 10.1097/JU.0000000000002928. Retrieved from https://pubmed.ncbi.nlm.nih.gov/36282060/
Zueger, R., Annen, H., & Ehlert, U. (2023). Testosterone and cortisol responses to acute and prolonged stress during officer training school. Stress, 26(1), 2199886. doi: 10.1080/10253890.2023.2199886. Retrieved from https://pubmed.ncbi.nlm.nih.gov/37014073/













