Oral Minoxidil

• Early results may be seen within a few months, but it could take longer to see the full effects

• You may experience shedding during the first few weeks of treatment. This is normal and shouldn’t cause you to worry. Extra shedding will resolve as the new hair grows in (usually in about a month)

• If you do not see improvement after 6 months of consistent use, you can message your provider to discuss adjusting your treatment plan

Common side effects can include low blood pressure (hypotension) and swelling in the legs (edema), among others. Some people experience headaches, although those typically improve over time. Others may experience additional hair growth on the face or body (hypertrichosis). This is the most common side effect of taking oral minoxidil, though the complaint is more common among women than men and is also more common when taking over 5 mg per day.

Side effects of oral minoxidil may be more pronounced when the drug is prescribed at higher doses. For full safety information (including the boxed warning) read through the Important Safety Information here.

Oral finasteride is an FDA-approved prescription hair loss treatment, while oral minoxidil is considered an off-label prescription for hair loss. This means oral minoxidil is not FDA-approved for that particular use, but a provider can still prescribe it if they deem it safe and appropriate for the patient.

Oral minoxidil may be preferred by men who do not want to risk the known slight chance of sexual side effects from taking finasteride. Oral minoxidil and oral finasteride have different mechanisms of action to tackle hair loss. Your provider will recommend a treatment based on your medical history, lifestyle, and any particular treatment preferences or side effect aversions you may have.

Topical minoxidil is an FDA-approved hair loss treatment that does not require a prescription whereas oral minoxidil is considered an off-label prescription for hair loss and does require a prescription. “Off-label” means it’s not FDA-approved for that particular use, but can still be prescribed at the provider’s discretion.

Topical and oral minoxidil contain the same active ingredient. While there have not been clinical studies comparing their efficacy, there appear to be some benefits of using an oral treatment method vs. a topical treatment method, such as more precise dosing and better treatment adherence & consistency.

Some people may also benefit less from topical minoxidil due to lower levels of a specific enzyme in their hair follicles (follicular sulfotransferase). Oral minoxidil may be an effective alternative in this case, as the medication is absorbed systemically and is thought to be activated by the liver.

Some people may get results from topical minoxidil but still want to consider oral minoxidil due to negative experiences with the topical such as scalp irritation, treatment running down your neck before you can rub it in, or the hassle of applying treatment two times a day.

Using both topical minoxidil and oral minoxidil at the same time will not produce better results and therefore, is not recommended.

• You may take oral minoxidil with or without food

• Consistent daily treatment is key to success, but oral minoxidil will not work better or faster if you take it more than once a day

• Oral minoxidil should be kept dry and at room temperature (between 68 and 77 degrees F) in the packaging provided by the pharmacy. Please keep it away from children and pets.