Important safety information
What you should know before taking Zepbound.
The fastest-working weight loss medication
Zepbound® prescription online for weight loss
At Ro, you’ve got options. Access the new Zepbound KwikPen, which ships directly to you, or check your insurance for the Zepbound pen and pick up at your local pharmacy.
A new way to access FDA-approved GLP-1s
The fastest way to lose weight, now at the lowest price ever*
Targets two hormone receptors to curb hunger
See safety info about GLP-1 medications.
What is Zepbound?
Zepbound contains tirzepatide—the same active ingredient as Mounjaro®. It’s an FDA-approved GLP-1 for weight loss in adults with obesity, or overweight with a weight-related condition, alongside diet and exercise. Now available as a multi-dose KwikPen or as a single-dose autoinjector pen.
How is Zepbound different from Ozempic® or Wegovy®?
Zepbound and Wegovy are approved by the FDA for weight loss, while Ozempic is approved for the treatment of type 2 diabetes, but can be prescribed off-label for weight loss, if appropriate.
The main difference between these medications is the active ingredient. Ozempic and Wegovy use semaglutide, while Zepbound uses tirzepatide. Tirzepatide is a dual-action GLP-1 and GIP, meaning it works by activating two receptors. In comparison, semaglutide activates the GLP-1 receptor only. Both Zepbound and Wegovy curb hunger and regulate your appetite, helping you feel full faster and longer.
What’s the difference between the Zepbound pen and the Zepbound KwikPen?
The Zepbound pen and KwikPen are the exact same FDA-approved medication in different delivery devices.
On average, people on Zepbound lose 20% of their weight in a year.
Key differences:
How it’s taken:
Zepound pen: Inject a new prefilled single-dose pen every week.
Zepbound KwikPen: Inject the same multi-dose pen with a new needle attachment every week for four weeks.
Pricing and insurance eligibility:
Zepbound pen: Ro checks for insurance coverage, or you can pay the list price.
Zepbound KwikPen: Cash pay only.
Fulfillment method:
Zepbound pen: Pick up at your local pharmacy.
Zepbound KwikPen: Shipped directly to you.
*When you pay cash for Zepbound KwikPen. Full weight loss results are seen at about 1 year, when combined with diet and exercise.
Safety info: GLP-1 medications are used to treat obesity or overweight (with weight-related problems), along with diet and exercise. They may have serious side effects, including possible thyroid tumors. Do not use if you or your family have a history of a type of thyroid cancer called MTC or MEN 2. See more serious warnings & safety info.
Select your current weight
252lbs
Weight you could lose (lbs):
50lbs
*Average weight loss in 1 year is 20% (compared to 3.1% with diet and exercise alone). Based on a 72-week clinical trial studying the highest doses of Zepbound in non-diabetic patients with obesity, or with overweight plus a weight-related condition, when paired with healthy lifestyle changes.
Your timeline to treatment
From personalized treatment to insurance support, we help you get—and stay—on track.
Start losing weight in 5 simple steps
1. Start your online visit
Answer a few questions about your health and goals, all online—no in-person doctor’s office visit necessary. You’ll find out if you’re eligible within 2 days.
2. Provider writes an Rx (if appropriate)
A provider will review your info and prescribe the right GLP-1 treatment for you, if eligible. Get ready for your first dose in two weeks if using insurance, or less than a week if paying cash.
3. Check your insurance coverage
Ro checks your insurance to see if GLP-1 coverage is available. If you require prior authorization, Ro's insurance concierge fights for coverage and submits all paperwork on your behalf. If you're covered, a prescription is sent to your pharmacy. If not, your provider will suggest alternative FDA-approved cash pay GLP-1 options. This process takes about 2-3 weeks.
4. Start your treatment
If paying cash, your medication ships right to your door and you can take your first dose in less than a week. If using insurance, your medication can be picked up at your pharmacy.
5. Get support to stay on track
Keep making progress with regular check-ins, expert guidance, and access to your care team 24/7. Ongoing care and support is there for you when you need it—whether it’s a quick chat with your provider or routine check-ins, we’re with you every step of the way.
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Meet our experts
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Zepbound FAQs
What’s the difference between the Zepbound pen and the Zepbound KwikPen?
The Zepbound pen and KwikPen are the exact same FDA-approved medication in different delivery devices.
On average, people on Zepbound lose 20% of their weight in a year.
Key differences:
How it’s taken:
Zepound pen: Inject a new prefilled single-dose pen every week.
Zepbound KwikPen: Inject the same multi-dose pen with a new needle attachment every week for four weeks.
Pricing and insurance eligibility:
Zepbound pen: Ro checks for insurance coverage, or you can pay the list price.
Zepbound KwikPen: Cash pay only.
Fulfillment method:
Zepbound pen: Pick up at your local pharmacy.
Zepbound KwikPen: Shipped directly to you.
Can I get Zepbound through Ro?
Yes! If you're interested in starting treatment with Zepbound—whether single-dose pens or KwikPen–the first step is completing an online visit so that a medical provider can determine if treatment is right for you. If you’re prescribed Zepbound KwikPen, it will be shipped directly to your door.
What are the side effects of Zepbound?
Like other GLP-1 medications, Zepbound comes with the risk of potential side effects. Most people experience these side effects when their dose is increased, and they tend to improve once a steady dose is reached. Some of the most common side effects include:
Nausea
Diarrhea
Vomiting
Constipation
Stomach pains
Upset stomach
Indigestion
Injection-site reactions
Fatigue
Belching and gas
Hair loss
Heartburn
Additionally, if you take oral birth control pills, talk to your healthcare provider before you use Zepbound. Birth control pills may not work as well while using Zepbound. Your healthcare provider may recommend another type of birth control for 4 weeks after you start Zepbound and for 4 weeks after each increase in your dose of Zepbound.
More severe side effects are rarer but possible. Serious side effects include:
Thyroid cancer: Zepbound may cause tumors in the thyroid, including thyroid cancer. Watch for possible symptoms, such as a lump or swelling in the neck, hoarseness, trouble swallowing, or shortness of breath. If you have any of these symptoms, tell your healthcare provider. Do not use Zepbound if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
Severe stomach problems
Pancreatitis
Gallbladder disease
Rapid heartbeat
Severe allergy (hypersensitivity)
Low blood sugar
Changes in vision in patients with type 2 diabetes
Kidney disease
Suicidal thoughts or behaviors
Pulmonary aspiration during general anesthesia or deep sedation: . In rare instances, some patients undergoing anesthesia during surgical procedures have had stomach contents enter their lungs, which can cause pneumonia and other problems.
You can report quality complaints and side effects to The Lilly Answers Center (TLAC) at +1(800) 545-5979 to notify Lilly, the manufacturer of your medication. They use side effect information to monitor and sometimes report on drug safety.
These are not all of the possible side effects of Zepbound. For more complete information about Zepbound, including Boxed warning, see full Important Safety Information.
How do you store Zepbound?
Store at 36–46°F in their original carton until you're ready to use them. Pens can be kept in the fridge until the expiration date on the label.
How much does Zepbound cost?
Using insurance? Zepbound pen may be covered by insurance.
Our insurance concierge will fight for your coverage and handle all of your paperwork.
Paying cash? The Zepbound KwikPen is available as a cash pay-only offering on Ro:
$299/mo for 2.5 mg dose
$399/mo for 5 mg dose
$449/mo for 7.5 mg, 10 mg, 12.5 mg, and 15 mg doses (with manufacturer offer)
More on the manufacturer offer: LillyDirect is offering the 7.5 mg, 10 mg, 12.5 mg, and 15 mg doses of Zepbound KwikPen at a discounted $449/mo price.
To keep this discounted price for 7.5 mg, 10 mg, 12.5 mg, and 15 mg refills you must complete your next refill check-in within 45 days of your last delivery.
What happens if you miss the 45-day window? You’ll be charged the full price for your refill:
$499 for a 7.5 mg refill
$699 for 10 mg, 12.5 mg, and 15 mg refills
We'll send you reminders to complete your refill check-in as the 45-day deadline gets closer.
Learn more about pricing here.
Additional $145/mo Ro membership fee required.
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