Key takeaways
Sildenafil (Viagra) may cause side effects like flushing, indigestion, dizziness, back pain, and more.
To reduce the side effects of sildenafil, your healthcare provider may adjust your dosage or recommend lifestyle changes like limiting alcohol.
Sildenafil side effects are typically mild and manageable, but if they persist, there are other erectile dysfunction (ED) treatment options to consider.
Here's what we'll cover
Key takeaways
Sildenafil (Viagra) may cause side effects like flushing, indigestion, dizziness, back pain, and more.
To reduce the side effects of sildenafil, your healthcare provider may adjust your dosage or recommend lifestyle changes like limiting alcohol.
Sildenafil side effects are typically mild and manageable, but if they persist, there are other erectile dysfunction (ED) treatment options to consider.
To reduce the side effects of sildenafil (Viagra), such as flushing, indigestion, and dizziness, ask your healthcare provider about adjusting your dosage, limit alcohol, stay hydrated, and consider making a few changes to how you take the medication.
Though sildenafil is a highly effective treatment for erectile dysfunction (ED), and most men tolerate it well, some may experience unpleasant side effects. If you’re wondering how to reduce side effects of sildenafil, keep reading for some helpful tips and alternative treatments to consider.
How to get rid of sildenafil (Viagra) side effects
If you are experiencing bothersome side effects from taking Viagra, talk to your healthcare provider. They may recommend taking a lower dose of the medication or suggest another type of treatment for your condition.
How to manage specific sildenafil side effects
For minor side effects, including flushing, indigestion, dizziness, or back and muscle pain, there are a few tips that may help you manage these symptoms:
Flushing: If you experience flushing, a reddening of the skin that often occurs on the face, neck or upper chest accompanied by a warm or hot sensation, try to cool down by opening a window, turning on a fan, or having a cold drink. It may also help to lie down for a bit and rest. If you are prone to hot flashes while taking Viagra, drinking alcohol can make this worse.
Indigestion: If you notice that Viagra upsets your stomach, try taking it with food, though it may mean the drug takes longer to work. While antacids can also help with indigestion, you can always ask your pharmacist for a more specific suggestion.
Dizziness: If you feel dizzy or lightheaded after taking Viagra, try sitting down or lying down flat until the lightheaded feeling passes. Try to get up slowly as the dizziness passes. While drinking plenty of fluids can help, drinking alcohol and smoking may make your dizziness worse.
Back or muscle pain: It can help to lie down or do gentle self-massage. Ask your pharmacist about over-the-counter pain relievers that can help as well.
In rare cases, more serious side effects can cause long-term complications. These include:
Vision changes: Viagra can sometimes cause temporary vision changes, such as a blue tinge to your vision, blurred vision, or light sensitivity. Dimming bright lights may help. While these side effects are usually mild and go away quickly, seek medical care right away if you experience vision loss in one or both eyes.
Low blood pressure: Viagra can lower your blood pressure after taking a dose, which can cause dizziness or lightheadedness. For most people, this is temporary and does not cause serious problems. To avoid low blood pressure while taking Viagra, it may help to stay hydrated by drinking plenty of nonalcoholic fluids in the hour before you take a dose.
Dosage and lifestyle adjustments
Your healthcare provider may recommend adjusting your dosage or making changes to your dietary habits and lifestyle if you’re experiencing side effects from sildenafil. The following may help:
Lowering your dose: A typical starting dose is 50 mg, but there are also doses of 25 mg and 100 mg available. Your healthcare provider may recommend lowering your dose if you’re experiencing side effects, as some of them, such as headaches, indigestion, and vision changes, appear to be dose-dependent.
Limiting alcohol: Drinking alcohol with sildenafil may increase the risk of side effects such as flushing, headache, dizziness, and low blood pressure. Limiting or avoiding alcohol around the time you take your medication may help reduce these effects.
Skipping grapefruit: Grapefruit juice can block the enzyme that breaks down sildenafil, causing the medication to build up in your bloodstream. This may increase the risk or severity of side effects like headache, flushing, dizziness, and low blood pressure.
Staying hydrated: Because sildenafil can lower blood pressure, staying hydrated may help reduce related dizziness or lightheadedness.
Avoiding heavy meals: Though you can take sildenafil with or without food, heavy, high-fat meals can delay the medication's absorption. If sildenafil causes indigestion for you, you may find it more comfortable to avoid a large meal around the time you take it.
How long do sildenafil side effects last?
Common side effects of sildenafil, such as headaches, flushing, and indigestion, are typically mild and temporary, often resolving within four hours as the medication leaves your system.
Most common side effects of sildenafil
Most people tolerate Viagra well, but like any medication, it has the potential to cause some side effects.
Common side effects of Viagra include:
Headache
Flushing
Indigestion
Nasal congestion (stuffy nose)
Back pain
Muscle pain
Nausea
Dizziness
Rash
Less commonly, some people experience mild and temporary vision changes, such as blue-tinged vision, blurred vision, and sensitivity to light.
Serious side effects of sildenafil
Rarely, serious side effects of Viagra can happen. If you experience any of the following, call your healthcare provider right away. If your symptoms feel life-threatening or you think you’re having a medical emergency, call 911.
Serious side effects of Viagra can include:
NAION, or non-arteritic anterior ischemic optic neuropathy: NAION is an eye condition that causes damage to your optic nerve that can cause a sudden loss of vision in one or both of your eyes. Viagra may increase the risk of vision loss in people with retinitis pigmentosa, an inherited disease of the retina.
Sudden decrease or loss of hearing: This condition may also involve other symptoms, such as tinnitus or dizziness.
Priapism: Priapism is a long-lasting (longer than four hours) and sometimes painful erection and is a medical emergency that needs to be treated immediately. Without treatment, this prolonged erection can cause permanent damage to the penis and irreversible ED.
Low blood pressure: This is generally only an issue if Viagra is taken with certain other medications that also increase the risk of low blood pressure.
Other treatments for ED
If, for some reason, you can’t get relief from Viagra’s side effects, rest assured there are several other treatments available for ED.
PDE-5 inhibitors
Viagra is just one of several PDE-5 inhibitors available to treat ED.These medications increase blood flow to the penis to support erections. Other options include:
Vardenafil (Levitra)
Avanafil (Stendra)
All of these oral medications work the same way as Viagra, by increasing blood flow to the penis and allowing for an erection in response to sexual stimulation. However, each of them varies in dosage, how long they work, and their side effects.
In addition to traditional tablets, PDE-5 inhibitors are also available in other formulations. For example, Ro Sparks is a fast-dissolving tablet combining sildenafil and tadalafil, the active ingredients in Viagra and Cialis. Another option is Ro's Daily Rise Gummies, a daily, low-dose tadalafil gummy that allows for more spontaneity.
Other medications
While PDE-5 inhibitors are the most common treatment for ED, other treatments are available. Other medications used to treat ED include:
Alprostadil self-injection: Alprostadil is an injectable medication, usually injected into the base or side of the penis. Each penis injection is dosed to create an erection lasting no longer than an hour, and because the needle used is very fine, pain from the injection site is usually minor.
Testosterone replacement therapy: In some men, ED may be caused by low levels of the hormone testosterone. In this case, testosterone replacement therapy (TRT) might be recommended.
Pumps and implants
If medications aren’t effective or appropriate for your ED, your healthcare provider may recommend one of the following treatments:
Penis pumps: A penis pump (aka vacuum erection device) is a hollow tube with a hand-powered or battery-powered pump. When the tube is placed over your penis, it is used to suck out the air inside the tube, creating a vacuum that pulls blood into the penis.
Penile implants: A penile implant is a surgical solution where a device is placed into both sides of the penis. These implants consist of either inflatable or malleable (bendable) rods. Inflatable devices allow you to control when and how long you have an erection.
Bottom line
No matter the cause of your ED, it can be a distressing source of emotional and psychological stress for both you and your partner. If you experience ED and can't tolerate the side effects of Viagra, there are many other ED treatments available to help you have a healthy and vibrant sex life.
Here’s what we know:
Most sildenafil side effects are mild and temporary. Common side effects like headache, flushing, indigestion, and dizziness usually improve as the medication wears off.
Simple changes may help reduce side effects. Lowering your dose, limiting alcohol, avoiding grapefruit, and staying hydrated may make it easier to tolerate.
Don't ignore serious symptoms. Seek medical care right away if you experience sudden vision or hearing loss, chest pain, or an erection lasting longer than four hours.
Frequently asked questions (FAQs)
What does sildenafil (Viagra) do?
Sildenafil (Viagra) is a prescription ED medication that belongs to a medication class called PDE-5 inhibitors. It works by increasing blood flow to the penis to support stronger erections when you're sexually aroused. Viagra typically starts working within 30–60 minutes, and its effects last 4–6 hours.
Do sildenafil side effects go away?
Yes, most sildenafil side effects, such as headaches, flushing, and indigestion, are typically mild and temporary, often resolving within about four hours as the medication wears off. If side effects don't resolve, your healthcare provider may recommend lowering your dosage or switching medications.
What are the worst side effects of sildenafil?
In rare cases, sildenafil can cause serious side effects, including vision loss, hearing loss, long-lasting, painful erections, and low blood pressure.
What percentage of men have side effects from sildenafil?
Most people tolerate sildenafil well, but side effects are fairly common. In clinical trials of men taking sildenafil as needed, the most common side effects of the typical 50 mg dose were headache (21%), flushing (19%), indigestion (9%), nasal congestion (4%), vision changes (2%), dizziness (4%), and rash (2%). Most of these side effects were mild and temporary.
Does sildenafil affect sleep?
Sleep problems aren't a common side effect of sildenafil. However, if you have obstructive sleep apnea (OSA), some research suggests that taking sildenafil before bed may worsen breathing problems during sleep. If you have OSA or another sleep disorder, ask your healthcare provider if sildenafil is a safe choice for you.
DISCLAIMER
If you have any medical questions or concerns, please talk to your healthcare provider. The articles on Health Guide are underpinned by peer-reviewed research and information drawn from medical societies and governmental agencies. However, they are not a substitute for professional medical advice, diagnosis, or treatment.
Viagra Important Safety Information: Read more about serious warnings and safety info.
Cialis Important Safety Information: Read more about serious warnings and safety info.
References
Andersson, K. E. (2018). PDE5 inhibitors - pharmacology and clinical applications 20 years after sildenafil discovery. British Journal of Pharmacology, 175(13), 2554–2565. doi: 10.1111/bph.14205. Retrieved from https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14205
DailyMed. (2024). Edex, alprostadil injection. Retrieved from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e8b8ec8d-1318-43e4-a182-446e9f9579de
Halls, J. E., Patel, D. V., Walkden, M., et al. (2012). Priapism: pathophysiology and the role of the radiologist. The British Journal of Radiology, 85 Spec No 1(Spec Iss 1), S79–S85. doi: 10.1259/bjr/62360925. Retrieved from https://www.birpublications.org/doi/10.1259/bjr/62360925
Karaarslan, C. (2020). Ocular Side Effects of Sildenafil That Persist Beyond 24 h-A Case Series. Frontiers in Neurology, 11, 67. doi: 10.3389/fneur.2020.00067. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC7019110/
Kim, J. N., Oh, J. J., Park, D. S., et al. (2019). Influence of Alcohol on Phosphodiesterase 5 inhibitors Use in Middle- to Old-Aged Men: A Comparative Study of Adverse Events. Sexual Medicine, 7(4), 425–432. doi: 10.1016/j.esxm.2019.07.004. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC6963111/
McMurray, J. G., Feldman, R. A., Auerbach, S. M., et al. (2007). Long-term safety and effectiveness of sildenafil citrate in men with erectile dysfunction. Therapeutics and Clinical Risk Management, 3(6), 975–981. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2387281/
National Institute of Diabetes and Digestive and Kidney Diseases. (2024). Definition & facts for erectile dysfunction. Retrieved from https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction/definition-facts
Neves, C., Tufik, S., Chediek, F., et al. (2010). Effects of sildenafil on autonomic nervous function during sleep in obstructive sleep apnea. Clinics (Sao Paulo, Brazil), 65(4), 393–400. doi: 10.1590/S1807-59322010000400008. Retrieved from https://pubmed.ncbi.nlm.nih.gov/20454497/
Nichols, D. J., Muirhead, G. J., & Harness, J. A. (2002). Pharmacokinetics of sildenafil after single oral doses in healthy male subjects: absolute bioavailability, food effects and dose proportionality. British Journal of Clinical Pharmacology, 53(Suppl 1), 5S–12S. doi: 10.1046/j.0306-5251.2001.00027.x. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC1874258/
Nivison-Smith, L., Zhu, Y., Whatham, A., et al. (2014). Sildenafil alters retinal function in mouse carriers of retinitis pigmentosa. Experimental Eye Research, 128, 43–56. doi: 10.1016/j.exer.2014.08.014. Retrieved from https://www.sciencedirect.com/science/article/abs/pii/S0014483514002383?via%3Dihub
Smith, B. P. & Babos, M. (2023). Sildenafil. StatPearls. from https://www.ncbi.nlm.nih.gov/books/NBK558978/
Troiano, G. & Lazzeri, G. (2021). The potential toxic combination of grapefruit juice and sildenafil. Toxin Reviews, 40(3), 334–337. doi: 10.1080/15569543.2019.1603163. Retrieved from https://www.tandfonline.com/doi/full/10.1080/15569543.2019.1603163
U.S. Food and Drug Administration (FDA). (2017). Highlights of prescribing information: Viagra (sildenafil citrate) tablets, for oral use. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020895s048lbl.pdf












