Semenax for male enhancement: does it work?

Felix Gussone, MD - Contributor Avatar

Reviewed by Felix Gussone, MD, Ro, 

Written by Gina Allegretti, MD 

Felix Gussone, MD - Contributor Avatar

Reviewed by Felix Gussone, MD, Ro, 

Written by Gina Allegretti, MD 

last updated: Oct 17, 2023

4 min read

Key takeaways

  • Semenax, a male enhancement supplement, claims to increase semen volume

  • There are no independent clinical trial data supporting the brand’s claims so far

  • Talk to a healthcare professional before starting any supplements, especially if you have underlying health conditions or take other medications

There’s no shortage of products that promise mind-blowing sex and explosive orgasms. One male enhancement supplement is Semenax, which supposedly boosts semen volume and ups the intensity of your orgasms.

But does it actually work? Can a natural supplement really transform your sex life? While Semenax advertises it can, the science so far is lacking. Here’s what you need to know.

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What is Semenax? 

Semenax is a male enhancement supplement that claims to increase semen volume and produce better orgasms. Leading Edge Health, the company that manufactures Semenax, advertises that the product can boost semen volume by roughly 20%.

It contains 18 natural ingredients including vitamin E, amino acids (like L-arginine and L-lysine), plant extracts, and mineral-rich components like pumpkin seeds. Semenax is manufactured and sold online by Leading Edge Health. It is not sold in stores. 

What is Semenax used for? 

If you are affected by erectile dysfunction, premature ejaculation, or your sexual performance isn’t quite where you want it to be, you might be searching for some type of natural solution.

The ingredients in Semenax are supposed to “feed your reproductive system” by encouraging the glands linked to semen production and ejaculation (the seminal vesicles, prostate, and bulbourethral gland) to produce more fluid. This increase in semen production is said to offer greater control of your ejaculations, intensify orgasms, and boost sexual satisfaction for you and your partners. 

One small unpublished study on the manufacturer’s website claims that Semenax increases the intensity of orgasms and produces more ejaculate than a placebo. Keep in mind that other than this study, there is no clinical trial data yet on Semenax to prove this. 

Does Semenax work?

While there are anecdotal reports about Semenax effectively increasing semen volume, there are no solid studies that support the brand’s claims. In order to answer the question “does Semenax work?”, one would would have to objectively study Semenax for effectiveness. So far, we don’t have reliable studies that answer the question. 

How long does it take Semenax to work? 

Using Semenax regularly is said to increase semen production in as little as two weeks. Some online customer reviews report even faster results. Other positive reviews boast that their semen volume more than doubled after using Semenax. But again, these reports are anecdotal and there’s no official answer backed by scientific evidence.

What’s in Semenax? 

So, what exactly is in Semenax that has the power to boost your semen volume? Let’s examine the evidence. 


Maca comes from the root of a plant called Lepidium meyenii. It’s in the same vegetable family as broccoli, cauliflower, and kale. 

Some research suggests that maca root can impact semen volume. One small study had nine men take maca for four months. Afterwards, the participants reported a larger amount of semen, higher sperm count, and better sperm motility. 

Another study found that males who took maca for three months had slight increases in sperm production, semen volume, and sperm motility, while those taking placebo saw no change. 


L-arginine is an amino acid that your body uses to make nitric oxide, a chemical crucial for increasing blood flow to the penis and promoting erections. 

Some research demonstrates that males with erectile dysfunction have low levels of L-arginine and suggests that supplementing it might improve symptoms. An analysis of 10 studies found evidence that L-arginine does help improve erectile dysfunction. 

There is some evidence that L-arginine has a positive impact on semen volume, but the data is only from animal studies. 

Horny goat weed

Epimedium sagittatum, commonly called horny goat weed, is an herb used in traditional Chinese medicine. It’s sometimes used as an aphrodisiac or found in supplements that treat ED. However, all of the current data comes from animal studies, so there isn’t much evidence it can enhance sexual function in humans. 

Muira puama

Muira puama, or Ptychopetalum olacoides, is an extract from tree bark in the Amazon rainforest. Evidence shows that it can increase libido, which is why it’s added to some sexual enhancement supplements. However, there are no studies that link it to increased semen volume. 

Pumpkin seeds and vitamin E

Some studies show supplementing with vitamin E and pumpkin seed oil improves semen quality. Again, the only evidence so far comes from animal studies. 

Other ingredients Semenax contains include:

  • L-lysine

  • L-carnitine

  • Swedish flower pollen

  • Avena sativa extract

  • Sarsaparilla root

  • Butea superba

  • Cranberry extract

  • Pine bark extract

  • Hawthorne berry

  • Zinc aspartate

  • Catuaba bark

How to take Semenax

Leading Edge Health recommends taking two Semenax pills twice a day (four pills total). They suggest taking the supplement for two months before deciding if you’re satisfied with the results.

Semenax side effects

Those taking Semenax might be wondering “Is Semenax Safe?”. Semenax is made from natural ingredients and no serious side effects have been reported, so far. However, just because a supplement is “natural,” it doesn’t mean it’s automatically safe. Supplements are only loosely regulated by the Food and Drug Administration (FDA) and the FDA doesn’t approve supplements for safety and effectiveness. This means that you can’t always be certain of the amount or quality of the product you’re consuming. 

Pros and cons of Semenax

The product can be ordered online and delivered directly to your home. The company offers a money-back guarantee if you’re not satisfied with your results. 

However, there are some disadvantages. One is cost. A one-month supply of Semenax costs up to $80––although the company does offer a discount if you purchase in bulk. You would need a minimum one-month supply anyway as they claim it takes a few weeks to start working. 

In addition, there is limited evidence that Semenax works. Although online reviews are generally positive, there are no published clinical studies demonstrating its safety and effectiveness. And since its components are natural supplements, most Semenax ingredients do not have U.S. Food and Drug Administration (FDA) regulations or guidelines for dosing.

Other options for ED

If your erections aren’t as hard or don’t last for as long as you’d like, there are plenty of treatment options available. Medications like Viagra (sildenafil) and Cialis (tadalafil) are FDA-approved for the treatment of erectile dysfunction.

Though an all-natural male enhancement pill that boosts semen volume and enhances orgasms sounds promising, there’s not much proof that it works. It may be helpful to talk to a healthcare professional before starting supplements like this, especially if you have any underlying health conditions or are taking other medications.

Viagra Important Safety Information: Read more about serious warnings and safety info.

Cialis Important Safety Information: Read more about serious warnings and safety info.


If you have any medical questions or concerns, please talk to your healthcare provider. The articles on Health Guide are underpinned by peer-reviewed research and information drawn from medical societies and governmental agencies. However, they are not a substitute for professional medical advice, diagnosis, or treatment.

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How we reviewed this article

Every article on Health Guide goes through rigorous fact-checking by our team of medical reviewers. Our reviewers are trained medical professionals who ensure each article contains the most up-to-date information, and that medical details have been correctly interpreted by the writer.

Current version

October 17, 2023

Written by

Gina Allegretti, MD

Fact checked by

Felix Gussone, MD

About the medical reviewer

Felix Gussone is a physician, health journalist and a Manager, Medical Content & Education at Ro.

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