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Curb cravings with prescription medication.
Prescription bupropion helps curb cravings and make nicotine less pleasurable.
Studies show best results from bupropion with at least 7 weeks of use, and even better results with 12 weeks of use.
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Quitter testimonials from our community
"In only 4 Days I didn’t feel the urge to pick up a cigarette or take a pull of my e-cigarette…at all! It’s been two weeks now and I am still smoke-free, cigarette free, and e-cigarette free."
Justin H, Zero Quitter, Boston
"I went from 15 years smoking, to 41 days not smoking and that’s huge. And I really thank Zero for that."
James N, Zero Quitter, East Stroudsburg, PA
"I'd still be smoking without Zero, plain and simple."
Mike S, Zero Quitter, New York, NY
Bupropion medical information
Bupropion is a smoking cessation aid that can help reduce nicotine cravings and withdrawal symptoms. For smoking cessation, bupropion is prescribed for a 12-week course. Learn more about bupropion, its potential benefits, and its potential side effects below.
How does it work?
The action of bupropion is not fully understood, but we know bupropion blocks the neurotransmitters dopamine and norepinephrine from being reabsorbed, which means they hang around and work longer. Bupropion seems to affect these these two important neurotransmitters in a way that is similar to nicotine, which can decrease your withdrawal symptoms when you are trying to quit. Bupropion also weakly blocks the nicotine receptor (the place on a nerve cell where a chemical lands to transmit its message), which makes smoking less appealing. This helps prevent relapse when former smokers are trying to make their new habit stick.
How is it used?
Bupropion should be started at least one week before you quit smoking. Bupropion should be taken once daily for the first 3 days, to allow your body to adjust. It should then taken twice daily for the 12 weeks.
What are the possible side effects?
The most common side effects of bupropion include: agitation, dry mouth, insomnia, headache/migraine, nausea/vomiting, constipation, tremor, dizziness, excessive sweating, blurred vision, tachycardia (rapid heart rate), confusion, rash, hostility, cardiac arrhythmia (irregular heartbeat), and auditory disturbance. Bupropion is generally very safe, but all medicines have the potential for causing side effects. Rarely, these can be serious, and you need to know about them. Bupropion has a black box warning about a potential for increased risk of suicidal thoughts and behaviors. This increased risk is seen in patients up to age 24. It’s important to remember that bupropion is primarily used as an antidepressant, and people with depression are at higher risk of suicidal thoughts and behaviors. However, it’s possible that bupropion taken for other reasons, like smoking cessation, might also have this increased risk. Learn more about bupropion, its potential benefits, and its potential side effects below.
Important safety information
What should you know before taking bupropion?
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Other ways to quit
The right treatment plan can make this the last time you quit smoking. Get physician-prescribed medication, if appropriate, to curb cravings and nicotine gum to reduce withdrawal symptoms.
Prescription bupropion is a smoking cessation aid that can help reduce nicotine cravings and withdrawal symptoms.
Nicotine gum is a nicotine replacement therapy (NRT) that can help reduce withdrawal symptoms like restlessness, irritability and anxiety.
Bupropion + gum
The combination of prescription bupropion and nicotine gum can increase your chances of successfully quitting by over 3x compared to cold turkey.