Key takeaways
Without insurance, the cost of a semaglutide can range from $129 (for compounded products) to nearly $1,850 (for brand-name versions) per month.
The exact amount you may pay for semaglutide depends on the specific brand-name drug prescribed (e.g. Ozempic, Wegovy, or Rybelsus), health insurance (if any), pharmacy, and location.
The list price of semaglutide varies, with Ozempic at $997.58 per month and Wegovy at $1,349.02 per month, but there are ways to reduce those costs, such as manufacturer savings cards.
Semaglutide can cost as little as $0 per month with insurance, depending on whether you’ve met your deductible and the semaglutide drug being prescribed.
Here's what we'll cover
Key takeaways
Without insurance, the cost of a semaglutide can range from $129 (for compounded products) to nearly $1,850 (for brand-name versions) per month.
The exact amount you may pay for semaglutide depends on the specific brand-name drug prescribed (e.g. Ozempic, Wegovy, or Rybelsus), health insurance (if any), pharmacy, and location.
The list price of semaglutide varies, with Ozempic at $997.58 per month and Wegovy at $1,349.02 per month, but there are ways to reduce those costs, such as manufacturer savings cards.
Semaglutide can cost as little as $0 per month with insurance, depending on whether you’ve met your deductible and the semaglutide drug being prescribed.
Semaglutide is a hot topic thanks to its positive impact on type 2 diabetes, weight loss, and more. But despite its growing popularity, some people may still assume it's too expensive and, thus, out of reach. In reality, there are multiple forms of the drug and many ways to save on the cost of semaglutide.
A month’s worth of semaglutide can range from $129 to nearly $1,850 if you’re paying out of pocket. The exact price depends on the specific drug prescribed (e.g. Ozempic, Wegovy, Rybelsus, or compounded semaglutide), insurance coverage (if any), and whether you use coupons or discount programs.
Keep reading to learn more about how much semaglutide costs with and without insurance—plus, tips for lowering the price of your prescription and alternative medications that may be worth discussing with your healthcare provider.
Ozempic Important Safety Information: Read more about serious warnings and safety info.
Wegovy Important Safety Information: Read more about serious warnings and safety info.
Rx weight loss with Ro
Get access to prescription weight loss medication online
How much does semaglutide cost without insurance?
Without insurance, semaglutide can cost between $129 (for compounded) and nearly $1,850 (for brand-name versions) per month. However, the list price for the brand-name forms of semaglutide ranges from $997.58.52 to $1,349.02 per month. Keep in mind that the list price just represents the original price that the drug manufacturer sets for the medication. It doesn’t account for insurance, dosage, discounts, or markups.
Before digging deeper, however, a quick refresher: Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist and the active ingredient in several brand-name, prescription medications, including Ozempic, Wegovy, and Rybelsus. While all three have been approved by the US Food and Drug Administration (FDA) and should be used alongside diet and exercise, they have different indications (i.e. FDA-approved uses).
They also vary in terms of dosage, strengths, and, you guessed it, cost. Regardless of brand name, semaglutide is thought to work the same way: by mimicking GLP-1, a hormone naturally found in your body that plays a key role in controlling blood sugar levels and regulating appetite.
Here’s a quick look at the cost of a one-month supply of semaglutide, by drug. For more details on the pricing for each drug, keep reading.
Drug | List price | Average pharmacy retail price |
---|---|---|
Ozempic | ||
Wegovy | ||
Rybelsus | ||
Compounded semaglutide | N/A | Varies (typically starts at $129) |
Now, let’s take a closer look at how much semaglutide costs without insurance for each formulation of the drug.
GLP-1 Important Safety Information: Read more about serious warnings and safety info.
Ozempic
At $997.58 per month as a list price, Ozempic is not cheap. That means that without insurance or discounts, it can cost about $249.40 weekly or up to $11,970.96 annually.
But these estimates are based on the list price. As with any medication, the cost of semaglutide can vary depending on several factors, including health insurance (if any), location, and pharmacy. Discount codes and savings programs can also impact the price you pay. For example, Novo Nordisk, the manufacturer of Ozempic, Wegovy, and Rybelsus, offers a patient assistance program for uninsured Americans or those on Medicare who meet certain eligibility criteria that are prescribed Ozempic for type 2 diabetes.
With that in mind, here’s how much an 8 mg/3 mL pen (2 mg dose) of Ozempic costs at different pharmacies, according to SingleCare.
Walgreens | $884.90 |
CVS | $905.27 |
Walmart | $915.25 |
RiteAid | $887.46 |
*While prices were valid at the time of publication, they may vary based on date and location. For the most accurate estimates, refresh the SingleCare searches and enter your zip code.
Wegovy
The list price of a 28-day supply of Wegovy is $1,349.02. That’s about $337.25 per week or $16,188.24 per year. If you don’t have insurance and are paying with cash, you can also get Wegovy for $499 per month through NovoCare, the manufacturer’s online pharmacy.
Unfortunately, Wegovy isn't part of Novo Nordisk’s patient assistance program. So, if you’re uninsured, coupons are likely your best bet for lowering the price of your prescription. But more on that later.
While, again, cost varies based on various factors, here's an idea of how much four 0.75 mL pens (each containing a 2.4 mg dose) cost, according to SingleCare.
Walgreens | $1,230.46 |
CVS | $1,300.46 |
Walmart | $1,331.48 |
RiteAid | $1,276.82 |
*While prices were valid at the time of publication, they may vary based on date and location. For the most accurate estimates, refresh the SingleCare searches and enter your zip code.
Rybelsus
Without insurance, a 30-count of 14 tablets of Rybelsus can set you back $997.58. Broken down, that’s about $249.40 per week, $35.63 per day (unlike Wegovy and Ozempic, you take Rybelsus daily), or up to $11,970.96 per year.
Similar to Ozempic, Novo Nordisk offers patient assistance to those who are uninsured or on Medicare. If program criteria are met, you can receive Rybelsus for up to 12 months at no cost.
Depending on location, pharmacy, and other factors, here’s the final price for a 30-count of 14 mg tablets, according to SingleCare.
Walgreens | $892.97 |
CVS | $946.54 |
Walmart | $946.66 |
RiteAid | $909.60 |
*While prices were valid at the time of publication, they may vary based on date and location. For the most accurate estimates, refresh the SingleCare searches and enter your zip code.
Compounded semaglutide
Compounded medications are custom-made pharmaceutical products by licensed pharmacists to meet a patient’s unique needs when a commercially available drug cannot. They are permitted to be prescribed under federal law. But they are not FDA-approved and do not undergo the same safety, effectiveness, and manufacturing review. That being said, a healthcare provider might prescribe a compounded drug when there’s a shortage or the patient is facing an insurance denial.
Enter, compounded semaglutide: a tailor-made medication that features the same active ingredient as the above brand-name semaglutide drugs of Ozempic, Wegovy, and Rybelsus. Compounded semaglutide (as with all compounded meds) isn’t covered by insurance. That said, it tends to be more affordable than paying out of pocket for a brand-name medication. Pricing generally starts at around $129 per month but varies depending on the provider.
Does insurance cover semaglutide?
When it comes to insurance, we have good and bad news. The good news? Ozempic, Rybelsus, and Wegovy may be covered, depending on your healthcare plan. The not-so-good news? All three are less likely to be covered by insurance companies when prescribed for weight loss.
To find out whether semaglutide is included in your insurance coverage, review your plan’s drug formulary, which lists all of the drugs covered by your plan. Novo Nordisk also offers tools to check insurance coverage for Wegovy, Rybelsus, and Ozempic.
If semaglutide is not listed, you or your healthcare provider can request prior-authorization from the insurance company, seeking approval for the medication based on medical necessity. If the prior-authorization is declined, you or your provider can then submit an appeal, writing a letter on your behalf requesting an exception.
Compounded semaglutide is not likely to be covered by insurance.
Does Medicaid cover semaglutide?
Each state determines what drugs Medicaid covers. To find out if any semaglutide drugs are covered in your area, refer to your plans’ formulary or contact your state Medicaid agency. To be covered by Medicaid, you must meet the income requirements set by your state.
Does Medicare cover semaglutide?
Medicare Part D drug plans and Medicare Advantage Prescription Drug Plans (MA-PD) are not required to cover specific drugs, such as Ozempic, Wegovy, or Rybelsus, However, they can cover these prescriptions, depending on the insurance provider and plan as well as the medical necessity as determined by the prescriber. Price depends on your plan’s copay and if you’ve met your deductible.
Currently, any Medicare plan, whether original or Medicare Advantage, is legally prohibited from covering medication prescribed for weight loss. There is a bill in the US Congress that may change this, and there are organizations advocating for its passage.
How to save on the cost of semaglutide
There’s no denying that the cost of semaglutide without insurance can be expensive. Novo Nordisk, however, offers a patient assistance program for Americans who are uninsured or on Medicare. If you qualify, you may be able to receive Ozempic or Rybelsus for type 2 diabetes at no cost.
Along with the patient assistance program, you can also take advantage of different pharmacy savings cards and coupons. All of the below options offer online databases, which you can use to determine whether your prescribed medication is eligible for discounts, how much you may be able to save, and where these savings are accepted.
Costco Membership Prescription Program: Membership program for Costco members that are uninsured or underinsured through which you can save up to 80% on drug costs depending on the medication, pharmacy, and your location. Program pricing only applies to in-person or mail-order prescriptions filled at Costco and at participating neighborhood pharmacies.
Optum Perks: Membership program that’s free and available to anyone no matter insurance coverage, if any, through which you can save up to 80% on most prescription drugs, depending on the medication, pharmacy, and your location. Optum Perks offers coupons—which are single-use and specific to individual drugs—as well as a pharmacy discount card—which is a general savings card that can be applied to a range of meds. Both of these can be used at over 64,000 pharmacies in the US.
WellRx: Membership program that’s free and available to anyone through which you can save up to 80% on drug prices, depending on the medication, pharmacy, and your location. Like Optum Perks, WellRx can be used with or without insurance. It also offers coupons for specific medications and a general discount card for various drugs—both of which can be used at 65,000 pharmacies nationwide.
GoodRx: Free service that offers coupons on various medications.
SingleCare: Free service that offers coupons on various medications.
Novo Nordisk also offers savings programs that might help lighten the financial load, though they’re typically reserved for patients with private or commercial insurance.
Ozempic: With the Ozempic Savings Card, you can pay as little as $25 for a one-, two- or three-month supply if you have insurance.
Wegovy: With the Wegovy Savings Card, you can pay as little as $0 for a 28-day supply of Wegovy if you have insurance. If you’re uninsured or pay cash for your prescriptions, the manufacturer offer caps the monthly cost of the drug at $499 per refill.
Rybelsus: With the Rybelsus Savings Card, you can pay as little as $10 for a one-, two-, or three-month supply if you have insurance.
How to get semaglutide
Semaglutide is a prescription drug, meaning you will need an Rx from a healthcare provider. You can schedule an appointment with your healthcare provider, who can assess if semaglutide is right for you.
Another option to get semaglutide is through Ro, which offers a comprehensive program that includes a prescription for branded semaglutide (depending on which is right for you) as well as coaching and insurance concierge support to help you get insurance coverage if you qualify.
Remember, the three brand-name semaglutide medications are FDA-approved for different uses. That said, all are typically prescribed in combination with diet and exercise, each one has a different FDA-approval.
Ozempic, for example, is FDA-approved for:
Controlling blood sugar in adults over 18 years old with type 2 diabetes mellitus
Reducing the risk of major cardiovascular health problems, such as heart attack, stroke, and death in adults with type 2 diabetes and heart disease
Reducing the risk of kidney disease progression in adults with type 2 diabetes and chronic kidney disease
Wegovy is FDA-approved for:
Chronic weight management in
Adults and children 12 years and older with obesity (which is commonly considered a body mass index (BMI) of 30 kg/m2 or greater)
Adults with overweight (typically defined as a BMI of 25 kg/m2 or greater) with at least one weight-related medical condition, such as type 2 diabetes, high blood pressure (hypertension), or high cholesterol
Reducing the risk of major cardiovascular health problems, such as heart attack, stroke, and death in adults with obesity or overweight and heart disease
Rybelsus is FDA-approved for:
Controlling blood sugar in adults over 18 years old with type 2 diabetes mellitus
Alternatives to semaglutide
There are no two ways around it: semaglutide can be expensive. But if you are struggling with the cost, there may be more affordable alternatives available. If your insurance won’t cover semaglutide or you’re paying cash for your prescription, consider asking your healthcare provider about these alternatives to Ozempic, Wegovy, and Rybelsus.
Tirzepatide
Tirzepatide is the active ingredient in the brand-name drugs Mounjaro and Zepbound. Both medications are once-weekly injections, and both come in the same dosage strengths. The key difference between them is what they’re approved to treat.
Like Wegovy, Zepbound is FDA-approved for chronic weight management in adults with obesity or adults with overweight and a weight-related health condition, such as high blood pressure, type 2 diabetes, or heart disease. It’s also FDA-approved for obstructive sleep apnea. Mounjaro, on the other hand, is FDA-approved for controlling blood sugar in adults with type 2 diabetes, similar to Ozempic and Rybelsus.
The list price of Mounjaro is $1,097.77 for a 28-day supply. Zepbound costs a bit less, at $1,086.37 for a 28-day supply. Certain doses of Zepbound are also available in single-dose vials for $349–$499 per month through Ro or LillyDirect, Eli Lilly’s self-pay pharmacy.
While price can vary by pharmacy and location, here’s an idea of how much four 0.5 mL pens (each containing a 5 mg dose) of tirzepatide costs, according to SingleCare.
| Mounjaro | Zepbound |
---|---|---|
Walgreens | $958.51 | $976.61 |
CVS | $1,015.92 | $1,035.48 |
Walmart | $1,037.06 | $1,056.80 |
RiteAid | $993.70 | $1,013.18 |
*While prices were valid at the time of publication, they may vary based on date and location. For the most accurate estimates, refresh the SingleCare searches and enter your zip code.
Eli Lilly, the maker of both Mounjaro and Zepbound, offers Savings Cards for both drugs. People with commercial drug insurance—with or without coverage for the medication—are eligible (other restrictions apply).
Mounjaro Savings Card: For people with coverage for Mounjaro, the savings card brings the cost down to $25 for a 28-day supply. For those without coverage, the savings card offers a maximum savings of up to $473 for a 28-day supply.
Zepbound Savings Card: For people with coverage for Zepbound, the savings card brings the cost down to $25 for a 28-day supply. For those without coverage, the savings card brings the cost down to $650 for a 28-day supply.
Neither Mounjaro nor Zepbound is part of Eli Lilly’s patient assistance program at this time.
Mounjaro Important Safety Information: Read more about serious warnings and safety info.
Zepbound Important Safety Information: Read more about serious warnings and safety info.
Metformin
Metformin (Glumetza, Fortamet) is an oral medication that treats type 2 diabetes by controlling blood sugar levels.
For example, here’s a quick look at the price of a 30-day supply of 500 mg extended-release tablets of generic metformin, according to SingleCare.
Walgreens | $19.40 |
CVS | $13.85 |
Walmart | $4.00 |
RiteAid | $19.61 |
*While prices were valid at the time of publication, they may vary based on date and location. For the most accurate estimates, refresh the SingleCare searches and enter your zip code.
Weight loss pills
For those taking semaglutide for weight loss, oral appetite suppressants can be an affordable alternative. The FDA has approved the following prescription weight loss pills for chronic weight management:
Phentermine/topiramate (Qsymia), taken once daily
Naltrexone/bupropion (Contrave), taken twice daily
Orlistat (Xenical), taken three times daily
While price can vary by pharmacy and location, here’s an idea of how much a 30-day supply of each medication costs, according to SingleCare.
| Qsymia | Contrave | Xenical |
---|---|---|---|
Walgreens | $181.63 | $172.27 | $223.23 |
CVS | $193.40 | $182.38 | $243.71 |
Walmart | $176.13 | $169.63 | $233.18 |
RiteAid | $181.32 | $165.06 | $223.47 |
*While prices were valid at the time of publication, they may vary based on date and location. For the most accurate estimates, refresh the SingleCare searches and enter your zip code.
Bottom line
Semaglutide can be a powerful tool for managing type 2 diabetes, chronic weight challenges, and other conditions, but it often comes with a steep price tag. So, how much is semaglutide?
Unfortunately, there’s no one set answer. But here’s the gist:
The cost of semaglutide varies based on the formulation prescribed (brand name or compounded), insurance coverage, pharmacy, and location. Since there’s no generic version, you can generally expect brand-name pricing, which typically means a higher cost.
Without insurance, a month’s supply of semaglutide is typically under $1,850. More specifically, the list price for Ozempic is $997.58, $1,349.02 for Wegovy, and $997.58 for Rybelsus.
While it tends to be more affordable than the brand-name, FDA-approved drugs, compounded semaglutide is not FDA-approved and is not usually covered by health insurance.
With insurance, the cost of semaglutide could drop to as little as $0, especially if you qualify for a manufacturer savings card. Pharmacy discounts and coupon cards, such as those available online, can also reduce the price of your prescription.
Frequently asked questions
How much is a 30-day supply of semaglutide?
Semaglutide’s cost depends on the specific drug (i.e. brand), your location, pharmacy, insurance coverage, among other factors. Keep in mind that discounts are available, and some Medicare and private health insurance plans help cover costs. That said, here are the list prices for about a month’s worth of each brand-name semaglutide drug, according to their manufacturer, Novo Nordisk.
Ozempic (2 mg/week): $997.58
Wegovy (2.4 mg/week): $1,349.02 or $499 through NovoCare online
Rybelsus (14 mg/day): $997.58
*List price for one month supply, according to Novo Nordisk. Your actual cost may vary depending on your location, pharmacy, insurance coverage, and eligibility for savings programs.
| Ozempic | Wegovy | Rybelsus |
---|---|---|---|
Dose | 2 mg/week | 2.4 mg/week | 14 mg/day |
Cost without insurance | $997.58 | $1,349.02 | $997.58 |
*List price for one month supply, according to Novo Nordisk. Your actual cost may vary depending on your location, pharmacy, insurance coverage, and eligibility for savings programs.
How can you get semaglutide for $25?
Depending on your insurance, you may be able to get semaglutide for $25 a month—or less. Novo Novdisk estimates most patients pay between $0-$25 out-of-pocket if insurance covers the prescription. For a better idea of what you’ll pay, refer to your insurance plan’s prescription coverage.
DISCLAIMER
If you have any medical questions or concerns, please talk to your healthcare provider. The articles on Health Guide are underpinned by peer-reviewed research and information drawn from medical societies and governmental agencies. However, they are not a substitute for professional medical advice, diagnosis, or treatment.
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